Immunotherapy has emerged as a promising treatment for certain types of lung cancer, particularly non-small cell lung cancers. Also known as biologic therapy or biotherapy, this approach involves using drugs to activate the immune system, prompting it to recognize and attack cancer cells.

In many cases, immunotherapy is considered early in the treatment journey, often immediately upon lung cancer diagnosis. However, it can also be used when other treatments have not produced the desired results.

Dr. Sumant Gupta, an expert oncologist, emphasizes, “Immunotherapy has revolutionized lung cancer treatment. We’ve seen remarkable success rates, especially with non-small cell lung cancers. It’s not just about survival; it’s about enhancing the quality of life for our patients. The advancements in this field give us hope and motivate us to explore new possibilities to improve outcomes and offer better care.”

Global statistics show that immunotherapy has significantly improved survival rates and quality of life for some lung cancer patients. Understanding the success rate of immunotherapy in lung cancer treatment is crucial for patients and healthcare providers.

This blog explores the effectiveness of immunotherapy, providing insights into its role in changing the landscape of lung cancer treatment.

How Does Immunotherapy for Lung Cancer Work?

Immunotherapy is a revolutionary approach to treating lung cancer by harnessing the power of your immune system.

Your immune system is your body’s defense against foreign invaders. It’s like an army that constantly patrols, seeking out and destroying harmful substances. Cancer cells can be tricky, often disguising themselves as normal cells to evade detection.

Immunotherapy unlocks your immune system’s full potential, training it to recognize and attack these disguised cancer cells. Recent FDA-approved drugs have paved the way for more effective and targeted treatments, offering hope and improved outcomes for lung cancer patients.

How Many Types Of Immunotherapy Are There?

Different types of immunotherapy work in various ways.

Immune checkpoint inhibitors
Your immune system uses a system of protein-based “checkpoints” to ensure it does not attack healthy cells. Certain proteins must be activated or deactivated to launch an immune system attack.

Cancer cells sometimes take advantage of these checkpoints to avoid being destroyed. Immunotherapy drugs that inhibit checkpoints make this much more difficult.

Monoclonal antibodies
Monoclonal antibodies are proteins made in a lab. They bind to specific parts of cancer cells and can carry medication, toxins, or radioactive substances straight to them.

Lung cancer vaccines
Cancer vaccines work in much the same way as vaccines for other diseases. They introduce antigens, foreign substances that trigger an immune system response against cells. Antigens can be used to attack cancer cells.

Other immunotherapies
Other immunotherapy drugs strengthen the immune system, making it more effective at fighting cancer cells.

What are the Success Rates and Life Expectancy?

Immunotherapy is still a relatively new treatment for lung cancer, with dozens of studies currently underway. So far, the results are promising.

In a 2020 study, researchers explored the effectiveness of immunotherapy and found a 7.1-month improvement overall for people treated with atezolizumab instead of chemotherapy.

A 2019 study found that the immunotherapy drug pembrolizumab led to durable antitumor activity and higher than estimated 5-year overall survival rates.

This 2018 study also sampled 616 people with advanced, untreated non-small cell lung cancer. Participants were randomly chosen to receive either immunotherapy or chemotherapy with a placebo.

The estimated 12-month survival rate among those who received immunotherapy was 69.2 percent. In contrast, the placebo group had an estimated 12-month survival rate of 49.4 percent.

Rajesh Kumar, a lung cancer patient, shares, “After undergoing immunotherapy for my lung cancer, I am grateful for the advancements in treatment. Thanks to Dr. Sumant and the team, I have renewed hope and improved quality of life.”

Another patient, Priya Sharma, expresses, “Immunotherapy has been a game-changer in my lung cancer journey. The personalized approach and care from Dr. Sumant have made all the difference. I am thankful for the progress in medical science that has given me a chance at a better life.”

What is the Cost of Immunotherapy Treatment in India?

The cost of immunotherapy treatments ranges from ₹ 1,00,000 to ₹ 5,00,000 or more (approximately $1,300 to $6,800) in India. However, the range varies depending on several factors, including the type of cancer, the specific immunotherapy drugs used, the duration of treatment, and the hospital or healthcare facility.

Multiple sessions over weeks or months may be required, significantly increasing the overall cost. Additionally, the cost may vary based on the patient’s response to treatment and any potential side effects that require management.

Thus, consulting a healthcare provider or hospital for an accurate estimate based on individual circumstances is advisable.

Conclusion

In conclusion, immunotherapy has revolutionized the treatment landscape for lung cancer, particularly non-small cell lung cancers. While individual responses vary, studies have shown promising results, with some patients experiencing long-term remission and improved quality of life.

Immunotherapy’s success lies in harnessing the body’s immune system to target and destroy cancer cells. Despite challenges, ongoing research and advancements continue to enhance the effectiveness of immunotherapy, offering hope to many lung cancer patients for a brighter, cancer-free future.

FAQs

1. Is immunotherapy effective for all types of lung cancer?

Immunotherapy is primarily used to treat non-small cell lung cancer (NSCLC), but it may also be used for small cell lung cancer (SCLC) in some instances.

2. What are the common side effects of immunotherapy for lung cancer?

Common side effects include fatigue, cough, shortness of breath, nausea, loss of appetite, skin rashes, and diarrhea. These side effects are manageable and improve after treatment.

3. Can immunotherapy be combined with other lung cancer treatments?

Yes, immunotherapy can be used alone or in combination with chemotherapy, radiation therapy, or targeted therapy, depending on the specific type and stage of lung cancer.

4. Are any specific tests required before starting immunotherapy for lung cancer?

Before starting immunotherapy, doctors may test whether the patient’s cancer cells express certain proteins or genetic mutations that make them more likely to respond. These tests help tailor treatment plans for better outcomes.

5. How long does immunotherapy treatment typically last for lung cancer?

The duration of immunotherapy treatment can vary depending on the individual’s response to treatment and lung cancer stage. Treatment may continue for several months or longer.

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